Sarcoma Research Getting Help from Utah Mice
Geneticists at the University of Utah have engineered mice that can develop synovial sarcoma, an aggressive soft-tissue cancer which most often strikes teenagers and young adults. A study conducted with these mice, genetically engineered with SYT-SSX2 fusion genes, has already provided researchers new information regarding the possible origin of synovial sarcoma tumors in humans. The study’s leader, Mario R. Capecchi, distinguished co-chair of human genetics at the University of Utah School of Medicine and an investigator with the Howard Hughes Medical Institute, says he also plans to study whether the gene must continue working for the tumor to advance. If so, the gene itself could be the key to developing new treatment options. Additional information regarding the study can be found in the April 2007 issue of the journal Cancer Cell.
Source: Medical News Today
Tags: genetic research
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