49 Saliva Proteins Identify Women With Breast Cancer
A study published in the January 10, 2008, edition of Cancer Investigation reports 49 proteins contained in saliva can reveal whether or not a woman has breast cancer.
The findings were obtained by researchers from the University of Texas Health Science Center at Houston who analyzed saliva samples from 10 healthy women, 10 women with benign breast tumors, and 10 women with ductal carcinoma in situ (DCIS).
After identifying approximately 130 different proteins contained in the saliva samples, the scientists used isotope labeling and mass spectrometry to compare each group’s sample. Their investigation found that 49 proteins expressed differently in women who had breast tumors.
Their results also indicate there’s a distinguishable difference between the saliva proteins of women with benign tumors and those with malignant ones.
The team believes this discovery could lead to new low cost screening methods which will make it easier to detect breast cancer in its early stages—possibly even during a routine dental appointment.
Source: Reuters
Related Links: UTHSC-H News Room; NewsLocale.org; CBC News; NCI Breast Cancer Surveillance Consortium
Related Podcast: Scientists Seek ‘Swish and Spit’ Test for Cancer from NPR
Tags: University of Texas Dental Branch; University of Texas Medical School; fibroadenoma; Houston, Texas; Proteomics Core Laboratory
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