Stanford Locates Human Progenitor Cell Linked to Leukemia
Scientists at the Stanford University School of Medicine have isolated a human blood cell involved in the creation of all blood cells found in the body.
This cell, called the multipotent progenitor, is the offspring of stem cells found in bone marrow. Later generations of progenitor cells become the red blood cells, platelets, and immune cells which comprise human blood.
Earlier studies involving mice indicate mutations in progenitor cells may trigger a blood cancer known as acute myelogenous leukemia, or AML. Isolating the progenitor cell in humans will enable scientists to further investigate its role in AML and other blood diseases.
The findings may also benefit future bone marrow transplant patients because progenitor cells can be used to produce all the body’s different blood cells in a lab dish.
If you’d like to learn more, results of the research have been published in Cell Stem Cell.
Source: Stanford Medical Center Report
Related Links: WOOD TV8; thaindian.com; The Leukemia and Lymphoma Society
Related Podcast - Leukemia: Clinical Trials with Dr Rob Stuart from the Medical University of South Carolina
Tags: Irving Weissman, MD; Ravindra Majeti, MD, PhD; Christopher Park, MD, PhD; Walter V. and Idun Y. Berry Foundation; NIH-funded; Palo Alto, CA; hematology; Stanford Institute for Stem Cell Biology and Regenerative Medicine; hematologic oncology
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