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	<title>Cancer Research Journal &#187; Bile Duct Cancer</title>
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		<title>Pro-Pharmaceuticals Reports Progress in Phase II Trials of Biliary Cancer Drug</title>
		<link>http://cancerresearchjournal.com/2007/07/25/pro-pharmaceuticals-reports-progress-in-phase-ii-trials-of-biliary-cancer-drug/</link>
		<comments>http://cancerresearchjournal.com/2007/07/25/pro-pharmaceuticals-reports-progress-in-phase-ii-trials-of-biliary-cancer-drug/#comments</comments>
		<pubDate>Wed, 25 Jul 2007 13:11:30 +0000</pubDate>
		<dc:creator>Lisa</dc:creator>
				<category><![CDATA[Bile Duct Cancer]]></category>
		<category><![CDATA[Chemotherapy]]></category>
		<category><![CDATA[Clinical Trials]]></category>
		<category><![CDATA[Gallbladder Cancer]]></category>
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		<description><![CDATA[Pro-Pharmaceuticals, Incorporated, (AMEX: PRW) is reporting promising preliminary results in their Phase II trial of a first-line treatment for biliary cancer. Participants in the study received the company&#8217;s developmental drug, DAVANAT, combined with another common anti-cancer agent, 5-FU. To date, four of the five patients who have received dosing have stabilized their disease with one [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.pro-pharmaceuticals.com/" rel="tag">Pro-Pharmaceuticals, Incorporated</a>, (<a href="http://finance.google.com/finance?q=PRW" rel="tag">AMEX: PRW</a>) is reporting promising preliminary <a href="http://www.pro-pharmaceuticals.com/press/pr-05-14-07.pdf" rel="tag">results</a> in their <a href="http://www.cancerhelp.org.uk/help/default.asp?page=73" rel="tag">Phase II trial</a> of a first-line treatment for <a href="http://www.debakeydepartmentofsurgery.org/home/content.cfm?proc_name=cancer+biliary+tract+gallbladder+bile+duct&#038;content_id=274" rel="tag">biliary cancer</a>. </p>
<p>Participants in the study received the company&#8217;s developmental drug, <a href="http://www.drugs.com/nda/davanat_070207.html" rel="tag">DAVANAT</a>, combined with another common anti-cancer agent, <a href="http://www.cancerhelp.org.uk/help/default.asp?page=4007" rel="tag">5-FU</a>.  To date, four of the five patients who have received dosing have stabilized their disease with one patient experiencing 35% <a href="http://training.seer.cancer.gov/module_cancer_disease/unit3_categories3_tumor_list.html" rel="tag">tumor</a> shrinkage.  </p>
<p>Encouraging results regarding the effectiveness of the DAVANAT, 5-FU treatment combination have already been shown during Phase I and II trials with <a href="http://www.plwc.org/portal/site/PLWC/menuitem.6067beb2271039bcfd748f68ee37a01d/?vgnextoid=14c6ea7105daa010VgnVCM100000ed730ad1RCRD&#038;vgnextfmt=cancer" rel="tag">end-stage</a> cancer patients.  </p>
<p>The first-line treatment study plans to include up to 42 patients at 6 sites and recruiting is still underway.  If you&#8217;d like additional information or are interested in participating in the trial, please visit <a href="http://clinicaltrials.gov/" rel="tag">www.clinicaltrials.gov</a> and type in the key word:  <a href="http://clinicaltrials.gov/ct/search;jsessionid=A392E8F8E033B03A4A110CD373AAA4B2?term=Davanat" rel="tag">DAVANAT</a>.</p>
<p>Source:  <a href="http://www.pro-pharmaceuticals.com/clincal-purpose1.htm" rel="tag">Pro-Pharmaceuticals, Inc</a></p>
<p>Related Video: <a href="http://www.youtube.com/watch?v=kR_WF2Fv1no" rel="tag">Pro-Pharmaceuticals DAVANAT Video</a> via <a href="http://youtube.com" rel="tag">YouTube</a>.</p>
<p>Related stories:  <a href="http://home.businesswire.com/portal/site/google/index.jsp?ndmViewId=news_view&#038;newsId=20070626006480&#038;newsLang=en" rel="tag">Pro-Pharmaceuticals reports receipt of notice from AMEX</a>; <a href="http://home.businesswire.com/portal/site/google/index.jsp?ndmViewId=news_view&#038;newsId=20070724005251&#038;newsLang=en" rel="tag">Pro-Pharmaceuticals submits plan of compliance to AMEX</a></p>
<p>Tags:  <a href="http://www.cancerbackup.org.uk/Cancertype/Bileduct/Bileductcancer" rel="tag">bile duct cancer</a>; <a href="http://www.tiscali.co.uk/reference/encyclopaedia/hutchinson/m0010119.html" rel="tag">polysaccharide</a>;     <a href="http://www.intute.ac.uk/sciences/cgi-bin/fullrecord.pl?handle=200433-13437" rel="tag">carbohydrate polymer</a>;     <a href="http://www.ansci.cornell.edu/plants/toxicagents/lectins/lectins.html#leccan" rel="tag">lectins</a>;     <a href="http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=43130" rel="tag">fluorouracil</a>; <a href="http://cholangiocarcinoma.org/" rel="tag">cholangiocarcinoma</a></p>
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