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Cancer Research Journal articles filed under Cancer Genetics

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Scientists See the Steps of Single Ribosomes

Article published on Friday 25 April 2008 at 11:59 am

A project led by the Lawrence Berkeley National Laboratory, the University of California, Berkeley and the University of California, Santa Cruz is allowing scientists to see individual ribosomes in action for the first time.
Ribosomes play an important role in the body by translating the genetic instructions carried by messenger RNA (mRNA). The ability to [...]

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STAT3 Inhibitors Can Help or Harm Glioblastoma Patients

Article published on Monday 3 March 2008 at 3:46 pm

A study led by the Harvard School of Medicine provides evidence that targeted chemotherapies commonly used to treat glioblastoma may do more harm than good for some patients.
Glioblastoma is a rare form of brain cancer with a poor survival rate. STAT3 inhibitors are one of the few therapies available to treat the disease, but [...]

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Canine Cancer Patients Benefit from Cliff Book

Article published on Friday 29 February 2008 at 8:10 am

An inspirational book is helping dogs with cancer receive expensive medical treatments their owners can’t afford to give them.
Cliff and I: My Dog’s Journey Through Cancer and Beyond chronicles the author’s personal experience helping her German Shepherd battle cancer.
As a tribute to her beloved pet, Cliff’s writer Joanne M. DeFluri is donating the proceeds [...]

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PI3K Signals Impact Breast and Ovarian Cancer Prognosis

Article published on Friday 25 January 2008 at 8:56 am

Researchers from the University of Minnesota and Duke University have discovered how specific proteins regulate genes responsible for turning cancer cells on or off in women with breast and ovarian cancers.
To arrive at their finding, the team studied 408 breast cancer patients and 153 ovarian cancer patients. Their investigation revealed that increased activity in [...]

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Northwestern Engineers Find a Faster Way to Separate DNA

Article published on Thursday 24 January 2008 at 7:28 am

Researchers from the McCormick School of Engineering at Northwestern University have developed a new technique for separating DNA which helps make the DNA sequencing process faster and less expensive.
McCormick’s innovative method brings scientists one step closer to a long sought-after goal — an affordable test that quickly determines an individual’s predisposition [...]

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Computational Biology Connects 480 Genes to Cell Division

Article published on Monday 14 January 2008 at 8:03 am

Scientists from Carnegie Mellon University, Hebrew University, the German Cancer Research Center in Heidelberg and the New York University School of Medicine have used computational biology techniques to identify 480 genes that control human cell division, including 118 that could contribute to cancer.
Rather than focusing on missing genes, this international team decided to concentrate on [...]

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Enzyme Determines Effectiveness of Tamoxifen Treatments

Article published on Monday 24 December 2007 at 8:14 am

Researchers from the University of Michigan and the Mayo Clinic have performed a study showing an inherited gene that lowers levels of a key enzyme may indicate whether Tamoxifen treatments will effectively treat women with a common type of breast cancer.
Tamoxifen is a Selective Estrogen Receptor Modulator (SERM) therapy prescribed to treat estrogen receptor positive [...]

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Kentucky Team Creates Cancer-Resistant Mice

Article published on Wednesday 19 December 2007 at 8:12 am

A team of researchers at the University of Kentucky have genetically engineered a group of mice that are highly resistant to cancer.
To accomplish this, the scientists introduced additional copies of tumor-suppressing genes called Par-4 into the fertilized eggs of mice and then implanted those eggs into cancer–prone surrogates. The genetically modified eggs produced offspring [...]

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New Research Institute Opens in Scotland

Article published on Tuesday 11 December 2007 at 8:15 am

The Institute of Genetics and Molecular Medicine (IGMM) has officially opened its doors in Edinburgh, Scotland.
The new institute brings together resources and funding from the Medical Research Council’s Human Genetics Unit, the Centre for Molecular Medicine, the Edinburgh Cancer Research Centre, and Cancer Research UK including more than 500 scientists involved in multidisciplinary studies on [...]

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Duke Scientists Identify Silenced Genes

Article published on Tuesday 4 December 2007 at 7:41 am

Researchers at Duke University have identified a large group of “silenced genes” which could help determine who will develop chronic diseases like cancer, diabetes or epilepsy.
These silenced genes, which scientists refer to as imprinted genes, can be inherited from either the mother or the father and only occur in animals which produce live births. [...]

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